The city and state of Northwest Germany is BREMEN, which is a 6 letter word. BREMEN is a city in the northwest of Germany and is the smallest of Germany's 16 states. It is located on the River Weser and is the second most populous city in the state. BREMEN is known for its port, which is one of the largest in Europe. The city is also home to several universities and museums. BREMEN is an important industrial and commercial center and is a popular tourist destination.