The crossword solution for the term CITY AFRICA is Lagos, a five-letter word. Lagos is the most populous city in Nigeria and the African continent as a whole. It is a major economic hub in West Africa, with a population of over 21 million people. The city is known for its vibrant culture, bustling markets, and diverse population. Lagos is also home to some of the most iconic landmarks in Africa, such as the National Museum of Nigeria and the National Theatre.