The term 'Change the Nature of' can be summarized by the word 'DENATURE, ' which is an 8-letter word. DENATURE is a process in which a substance or material is altered from its natural state, often to make it more suitable for a specific purpose. For example, denaturing proteins can make them easier to digest or more resistant to certain environmental conditions. Denaturing can also refer to the process of changing the chemical composition of a substance, such as adding a solvent or other chemical to make it less volatile or more stable.