The term 'Central Significance' can be summarized as having a major importance or relevance. It is often used to describe something that is of great importance to a particular situation or context. The word 'GIST' is an acronym for 'General Idea, Summary, or Theme, ' which is a concise way of summarizing the main points of a topic. Therefore, the term 'Central Significance' can be seen as the main point or theme of a particular situation or context.