The term 'CENTER OF OPERATIONS' can be described by several crossword solutions, including HUB (3 letters), BASE (4 letters), HOMEBASE (8 letters), MEDSCHOOL (9 letters), and HOMEOFFICE (10 letters). A HUB is a central point from which other things originate or are managed. A BASE is a location from which operations or activities are managed. Homebase is a place where one lives and works, such as a home office. Medschool is a medical school, which is a center of operations for medical education and research. Homeoffice is a place where one works from home, such as a home office. All of these terms describe a center of operations, which is a place where activities are managed or coordinated.