The term 'Cause of Strain Pain' can be summarized by the crossword solution of 'HERNIA'. HERNIA is a medical condition in which an organ or tissue protrudes through the wall of the cavity that normally contains it. It is caused by increased pressure in the abdomen, which can be due to straining during physical activity, lifting heavy objects, or coughing. HERNIA can cause pain and discomfort, and may require surgery to repair.