Cause of fatigue can be attributed to a variety of factors, including ANEMIA (6 letters). ANEMIA is a condition in which the body does not have enough healthy red blood cells to carry oxygen throughout the body. This lack of oxygen can cause fatigue, as well as other symptoms such as shortness of breath, pale skin, and dizziness. ANEMIA can be caused by a number of different factors, including iron deficiency, vitamin deficiencies, and chronic diseases. Treatment for ANEMIA typically involves taking iron supplements or other vitamins, as well as making lifestyle changes such as eating a balanced diet and exercising regularly.