The capital of Syracuse is ESS, which stands for Syracuse, New York. Syracuse is the fifth most populous city in the state of New York and the county seat of Onondaga County. It is located in the central part of the state, on the shores of Onondaga Lake. The city has a rich history, having been founded by the ancient Greeks in 734 BC. It was an important trading center during the Roman Empire and was later occupied by the French and British. Today, Syracuse is home to a number of universities, including Syracuse University, and is a major cultural and economic hub in the region.