The capital of Macedonia is Skopje, a city with a population of around 500, 000 people. It is located in the northern part of the country and is the political, economic, and cultural center of Macedonia. Skopje has been an important city since the 4th century BC, when it was part of the Roman Empire. It has also been an important trading center for centuries, and today is home to many universities, museums, and other cultural attractions.