The term 'by the shortest and most direct route' can be represented by two crossword solutions: BEELINE (7 letters) and BEELINES (8 letters). BEELINE is a noun that refers to a route that is the most direct and efficient way of getting from one place to another. BEELINES is the plural form of BEELINE, which means multiple routes that are the most direct and efficient way of getting from one place to another. This term is often used in navigation and transportation, as it is important to take the most efficient route when travelling.