Buster Drug is a term used to refer to a type of drug that was popular in the 1920s and 1930s. The crossword solutions for this term are NARC (4 letters), KEATON (6 letters), CRABBE (6 letters), and NARCO (5 letters). NARC is an acronym for Narcotics Anonymous, a 12-step program for people struggling with addiction to drugs. KEATON is a reference to the actor Buster Keaton, who was known for his comedic roles in silent films. CRABBE is a reference to the actor and swimmer Johnny Weissmuller, who played Tarzan in the 1930s and 1940s. Finally, NARCO is a shortened form of the word Narcotics, which refers to drugs that are illegal or heavily regulated.