Burr and Hamilton were two of the most famous political rivals in American history. They were both prominent figures in the early days of the United States, with Burr serving as Vice President under Thomas Jefferson and Hamilton as the first Secretary of the Treasury. Their rivalry culminated in a duel in 1804, in which Hamilton was fatally wounded. The term 'Burr and Hamilton' can be used to describe their relationship, and can also be summarized as 'ENEMIES' or 'FOES'.