Brother Esau is a figure in the Bible, who was the TWIN brother of JACOB and the son of Isaac and Rebekah. He was also known as Edom, which is the name of the region he ruled over. The Edomites were the people of Edom, and Adah was his wife. In summary, the crossword solutions for Brother Esau are JACOB (5 letters), Edom (4 letters), Isaac (5 letters), Edomites (8 letters), Edomite (7 letters), and Adah (4 letters), TWIN (4 letters).