Biscotto flavoring is a popular Italian cookie flavoring that can be made with a variety of ingredients. The four crossword solutions for biscotto flavoring are ANISE (5 letters), aniseed (7 letters), ORANGE (6 letters) and LIME (4 letters). ANISE is a licorice-like spice that is used to flavor many Italian desserts, including biscotti. Aniseed is the seed of the ANISE plant, which has a similar flavor. ORANGE and LIME are both citrus fruits that are often used to add a zesty flavor to biscotti.