The term 'BIG COSMETICS CHAIN' can be summarized by the crossword solution ULTA, which is a four-letter acronym for Ulta Beauty. Ulta Beauty is an American chain of beauty stores that offers cosmetics, fragrances, skincare, haircare, and salon services. Founded in 1990, it has grown to become one of the largest beauty retailers in the United States, with over 1, 200 stores across the country.