Barrymore Actress is a term used to refer to two of the most famous members of the Barrymore family, DREW and Ethel. DREW Barrymore is an American actress, producer, director, author, model, and entrepreneur who began her career as a child actor in 1982. She is best known for her roles in films such as E.T. the Extra-Terrestrial, Charlie's Angels, and The Wedding Singer. Ethel Barrymore was an American stage and film actress who was one of the most celebrated leading ladies of the early 20th century. She won an Academy Award for Best Supporting Actress for her performance in None But the Lonely Heart in 1944.