ACCUTANE TARGET is a term used to describe the people who are most likely to benefit from taking the drug Accutane. Accutane is a medication used to treat severe ACNE, and it is most effective in people with moderate to severe cases of ACNE. The two crossword solutions for ACCUTANE TARGET are ACNE (4 letters) and ZIT (3 letters). ACNE and ZIT are both terms used to describe the skin condition that Accutane is used to treat.