Zinc OXIDE ointment is a topical medication used to treat skin conditions such as diaper rash, eczema, and psoriasis. It is made from zinc OXIDE, which is a mineral that has antiseptic and astringent properties. The ointment works by forming a protective barrier on the skin, which helps to soothe irritation and reduce inflammation. It can also be used to protect the skin from further damage caused by exposure to the sun or other environmental factors.