The crossword solution for the term 'Wrangler Relative' is 'CHEROKEE'. The CHEROKEE are a Native American tribe that originally inhabited the area that is now the southeastern United States. They are one of the five 'civilized tribes' and are the largest Native American tribe in the United States. The CHEROKEE language is part of the Iroquoian language family. The CHEROKEE Nation is the largest federally recognized tribe in the United States, with over 300, 000 citizens.