The term WEN can be solved in two ways in a crossword puzzle. The first solution is GROWTH, which is a 6-letter word that refers to the process of increasing in size or number. It is often used to describe the development of a person, business, or other entity. The second solution is CYST, which is a 4-letter word that refers to a closed sac or capsule containing fluid or semisolid material. It is typically found in the body and can be caused by a variety of conditions.