Vexation is a feeling of ANNOYANCE, IRRITATION, or distress caused by something that is difficult to deal with. The crossword solutions for the term VEXATION include DISAPPOINTMENT (14 letters), IRRITATION (10 letters), AGGRAVATION (11 letters), INCONVENIENCE (13 letters), EXASPERATION (12 letters), HARASSMENT (10 letters), DISCONTENT (10 letters), GRIEF (5 letters), BOTHER (6 letters), DISCOMFORT (10 letters), DISPLEASURE (11 letters), ANGER (5 letters), ANNOYANCE (9 letters), PEST (4 letters), IRE (3 letters), CHAGRIN (7 letters), FRET (4 letters), ITCH (4 letters), PAIN (4 letters), SNIT (4 letters), and PEEVE (5 letters). These words all describe different levels of vexation, from mild ANNOYANCE to extreme distress.