The term UPPER REGIONS is composed of two crossword solutions, ETHER and SKIES. ETHER is a five letter word meaning the clear, colorless, odorless, gaseous form of matter that surrounds the earth and other planets. SKIES is also a five letter word meaning the atmosphere or expanse of air surrounding the earth, which is visible as clouds, rain, snow, etc. Together, these two words can be used to describe the upper regions of the atmosphere, which are located above the clouds and contain the ozone layer.