The term 'botches up' can be broken down into three separate crossword solutions: LOUSES (6 letters), GUMS (4 letters), and messes (6 letters). LOUSES are small, wingless insects that feed on the blood of mammals and birds. They are also known to cause skin irritation and itching. GUMS are a type of soft tissue found in the mouth that helps to hold teeth in place. Messes are a state of disarray or disorder, often caused by carelessness or negligence. Together, these three words form the phrase 'botches up, ' which means to make a mistake or do something badly.