The crossword solutions for the term UP AND ___! are ABOUT (5 letters) and COMER (5 letters). The term UP AND ___! is a phrase that is often used to express enthusiasm or excitement. It is usually used to emphasize the importance of something or to show that someone is ready to take action. The word ABOUT suggests that the person is ready to learn more ABOUT the topic or situation, while the word COMER implies that the person is ready to take action and come to the aid of others.