Uncontrollable Twitch is a term used to describe a SPASM, which is an involuntary and sudden muscle contraction. It is usually caused by a neurological disorder or a reaction to certain medications. The term is also used to describe a sudden, uncontrollable movement of the body or limbs. This type of movement can be caused by a variety of medical conditions, including epilepsy, multiple sclerosis, and Parkinson's disease.