The term 'toe lead-in' is a crossword solution for the word 'TICTAC, ' which is a six-letter word. It is a term used in the game of tic-tac-toe, referring to the first move made by a player in the game. Toe lead-in is the first move that a player makes in the game, usually by placing an X or O in one of the nine squares on the board. This move sets the tone for the rest of the game and can be used strategically to gain an advantage over the opponent.