Throat trouble is a common medical issue that can be caused by a variety of factors. Two of the most common causes are a FROG in the throat, which is a feeling of tightness or a lump in the throat, and strep throat, which is an infection caused by bacteria. Both of these conditions can cause pain, difficulty swallowing, and other symptoms. Treatment for throat trouble depends on the underlying cause, but may include antibiotics, anti-inflammatory medications, or lifestyle changes.