The crossword solutions for the term THE LAST OF US are ESS, which stands for the post-apocalyptic action-adventure video game developed by Naughty Dog and published by Sony Computer Entertainment. The game follows protagonists Joel and Ellie as they travel across a post-apocalyptic United States in an attempt to find a cure for a mutated strain of the Cordyceps fungus. It was released in 2013 and has since become one of the most critically acclaimed video games of all time.