The Big Easy Acronym is an acronym for the city of New Orleans, Louisiana, which is often referred to as 'NOLA'. NOLA is a four-letter acronym that stands for New Orleans, Louisiana. The Big Easy is a nickname for New Orleans, and it is used to refer to the city's laid-back atmosphere and culture. The city is known for its vibrant music, food, and nightlife, and it is a popular tourist destination.