The term 'Takes Effect' can be broken down into two crossword solutions: TELLS (5 letters) and SETSIN (6 letters). TELLS is a verb meaning to communicate information to someone, usually in the form of speech. SETSIN is a verb meaning to establish or institute something, usually a law or rule. Together, these two words can be used to describe the process of enacting a law or rule, which is what 'Takes Effect' means.