Take Charge' is an expression that means to take control of a situation. The crossword solutions for this term are ionize (6 letters), HEAD (4 letters), LEAD (4 letters), and runtheshow (10 letters). Ionize means to break down into ions, which are electrically charged particles. HEAD is a verb meaning to be in charge or to LEAD. LEAD is also a verb meaning to direct or guide. Run the show is an idiom meaning to be in control of a situation.