The term 'SPRAIN SITE' is a crossword solution that refers to the ANKLE, which has five letters. The ANKLE is a joint in the body where the leg and the foot meet. It is made up of three bones, the tibia, fibula, and talus, and is held together by ligaments, tendons, and muscles. Sprains occur when these ligaments are stretched or torn, causing pain and swelling. The ANKLE is a common site for sprains, as it is often twisted or turned in an unnatural way.