A soothing agent is a substance that can be used to reduce pain, inflammation, and irritation. The crossword solutions for the term 'soothing agent' are BALM (4 letters), EMOLLIENT (9 letters), aloe (4 letters), SALVE (5 letters), and ANODYNE (7 letters). BALM is a fragrant ointment used to heal or soothe the skin. EMOLLIENT is a substance that softens and moisturizes the skin. Aloe is a plant with thick leaves that contain a gel-like substance that is often used to soothe skin irritations. SALVE is a healing ointment used to treat minor cuts, burns, and other skin irritations. ANODYNE is a drug or other substance that relieves pain.