The crossword solution for the term 'Snake in 'Antony and Cleopatra' is ASP, which stands for aspis, a venomous snake. In William Shakespeare's play 'Antony and Cleopatra', the aspis is used by Cleopatra to commit suicide. The aspis is mentioned in Act 5, Scene 2 of the play, when Cleopatra says, 'Give me my robe, put on my crown; I have Immortal longings in me.' She then orders her servant to bring her an aspis, which she uses to end her life.