The term SMARTY can be broken down into three crossword solutions: BRAIN (5 letters), WISEACRE (8 letters), and CLAUDEBRAINS (12 letters). BRAIN is a noun that refers to the organ in the head of humans and other animals that is responsible for thought, memory, emotion, and other mental processes. WISEACRE is an informal term for someone who is overly clever or wise, often in a way that is annoying. CLAUDEBRAINS is a humorous combination of the words 'Claude' and 'BRAINS, ' suggesting a person who is very intelligent. All three terms can be used to describe someone who is smart or intelligent.