Slough off is a phrase that means to SHED or discard something, usually in a figurative sense. The term can be broken down into two crossword solutions: SHED (4 letters) and MOLT (4 letters). SHED is a verb that means to get rid of something, either physically or metaphorically. MOLT is a verb that means to SHED feathers, fur, skin, or an outer layer, usually as part of a natural process. Together, these two words form the phrase 'slough off, ' which is used to describe the act of discarding something.