Sioux City Citizens are Iowans, as the 6-letter crossword solution suggests. Sioux City is a city in the northwest corner of Iowa, located on the Missouri River. It is the fourth largest city in the state and is home to many Iowans. The city has a rich history, having been founded in 1854 by settlers from the Sioux tribe. Today, Sioux City is a vibrant and diverse community, with a population of over 82, 000 people. Its citizens are proud to call themselves Iowans and take pride in their city's heritage.