The crossword solution for the term SIN, DEPRAVITY is VICE, which is a four-letter word. VICE is an immoral or wicked behavior, especially when it is habitual. It is often used to describe activities that are considered contrary to accepted moral standards. Examples of VICE include gambling, drug use, and sexual promiscuity. VICE is often seen as a form of depravity, as it involves engaging in activities that are considered immoral or wrong.