The Second First Lady of the United States was ABIGAIL Adams, wife of John Adams, the second President of the United States. ABIGAIL Adams was a strong advocate for women's rights and was an influential figure in the early days of the United States. She was also a prolific letter writer, and her correspondence with her husband is still studied today. ABIGAIL Adams was the first woman to be both the wife of a President and the mother of a President, as her son John Quincy Adams became the sixth President of the United States.