The term 'Second Beginning' can be represented by the crossword solution NANO, which is an acronym for 'New Approach to Novel Opportunities'. This phrase was coined by the British Prime Minister Tony Blair in 2004 to describe his vision of a new era of economic growth and prosperity. It was intended to signify a shift away from traditional economic models and towards a more innovative approach to business and industry. NANO has since become a popular term used to describe the concept of a second beginning or fresh start.