Saturate with is a phrase that can be used to describe the process of immersing something in a liquid or other substance. The two crossword solutions for this phrase are 'IMBUE' and 'steepin'. IMBUE is a verb meaning to fill or permeate something with a feeling or quality, while steepin is an adjective meaning to be soaked or drenched in a liquid. Both words can be used to describe the process of saturating something with a substance.