The crossword solution for the term 'Role for Keanu' is NEO, a three-letter word. NEO is the character Keanu Reeves portrayed in the science fiction action film The Matrix (1999). He is a computer programmer who is drawn into a rebellion against machines who have taken over the world and placed humanity inside a simulated reality. NEO is a hacker and computer hacker who is able to manipulate the Matrix and use superhuman abilities to fight against the machines.