The crossword solution for the term 'REMOVE THE OUTER LAYER' is SKIN. SKIN is the outermost layer of the human body, and it serves as a protective barrier against environmental factors such as bacteria, viruses, and other pathogens. It also helps regulate body temperature and protect against dehydration. Removing the outer layer of SKIN can be done for medical reasons, such as to treat SKIN conditions or to remove a mole or wart. It can also be done for cosmetic reasons, such as to reduce wrinkles or to remove tattoos.