The term 'really run-down' can be described by two crossword solutions: SEAMY (5 letters) and DECREPIT (8 letters). SEAMY is an adjective that means morally disreputable or sordid. It is often used to describe a place or situation that is unpleasant or corrupt. DECREPIT is an adjective that means worn out or deteriorated due to age or neglect. It is often used to describe something that is in a state of disrepair or dilapidation. Together, these two words provide a vivid description of something that is really run-down.