The term 'READY FOR THE CHALLENGE' can be broken down into two crossword solutions: GAME (4 letters) and UPTOIT (6 letters). The term 'GAME' is often used to refer to a form of entertainment or competition, usually involving physical or mental skill. It can also refer to a particular instance of such an activity. The term 'UPTOIT' is an informal phrase meaning to be prepared for a challenge or task. Together, these two terms suggest that someone is prepared to take on a challenge or GAME.