Rabies is a viral disease that affects the central nervous system of mammals, including humans. It is caused by the rabies virus and is usually transmitted through the bite of an infected animal. The most common symptom of rabies is HYDROPHOBIA, which is an intense fear of water. This is due to the paralysis of the throat muscles, which makes it difficult to swallow. Another symptom of rabies is lyssa, which is an uncontrollable rage or frenzy. It is believed to be caused by the virus attacking the brain.