The crossword solution for the term 'Queen with a 'LACE'' is ANNE, which is a four-letter word. ANNE was the Queen of England and Ireland from 1702 to 1714. She was the second daughter of James II and VII and the last monarch of the House of Stuart. During her reign, she was known for her patronage of the arts and her support of the Church of England. She was also known for her LACE-making skills, which she used to create intricate designs for her gowns and other garments.