The two crossword solutions for the term 'Queen of the Nile' are NEFERTITI (9 letters) and CLEO (4 letters). Nefertiti was an Egyptian queen who ruled alongside her husband, Pharaoh Akhenaten, during the 14th century BC. She is often referred to as the most beautiful woman in ancient Egypt and is depicted in many works of art. Cleopatra was the last active ruler of the Ptolemaic Kingdom of Egypt and is one of the most famous female rulers in history. She was a member of the Ptolemaic dynasty, a family of Greek origin that ruled Egypt after Alexander the Great's death in 323 BC.