Pueblo dwellers are Native American tribes that live in the southwestern United States. The Hopi, Zuni, and other Pueblo tribes have inhabited the region for centuries. The Hopi, with four letters, are a tribe of Native Americans who primarily inhabit northeastern Arizona. The Hopis, with five letters, are the descendants of the Hopi tribe. The Zuni, with four letters, are a tribe of Native Americans who primarily inhabit western New Mexico.