Psycho Co-Star refers to two actors who starred in the classic 1960 Alfred Hitchcock film, Psycho. Janet Leigh played the role of Marion Crane, a woman on the run from the law after stealing money from her employer. Vera Miles played the role of Lila Crane, Marion's sister who is determined to find out what happened to her. Both Leigh and Miles gave remarkable performances in the film, which has become an iconic part of cinema history.